Anti-Tissue Transglutaminase
Investigation : Anti-Tissue Transglutaminase
Spec container : Serum Gel 
Volume required : 5 ml
Reference range : <7.0 U/ml
Turnaround : <3 days

Methodology: Enzyme Immunoassay using human recombinant antigen.

Indications: As an aid in the diagnosis of gluten-sensitive enteropathies such as coeliac disease and dermatitis herpetiformis

Protocol: Samples are screened for IgA-specific anti-tissue transglutaminase (tTG). Positive tests are confirmed by IgA immunofluorescence using endomysium. Total IgA is measured to exclude IgA deficiency. If IgA deficiency is present then IgG-specific antibodies are performed by immunofluorescence using endomysium.

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Anti-endomysial antibody demonstrated by immunofluorescence


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