Investigation : FIP1L1-PDGFRA
Specimen type : Bone marrow or blood
Spec container : EDTA 
Volume required : 2ml of bone marrow or 10ml of blood
Turnaround : 21 days
Samples should arrive within the laboratory within 72 hours of collection.

If sample cannot be sent immediately after bleeding, keep in 4 degree fridge and send as soon as possible.

FIP1L1-PDGFRA fusion gene is present in approximately 10-15% of patients with hypereosinophilic syndrome (HES). Since PDGFRA is a therapeutic target of tyrosine kinase inhibitor imatinib, patient with FIP1L1-PDGFRA fusion gene are dramatically sensitive to treatment with imatinib.

Contact HODS Molecular Biology Lab for further enquiries on Ext. 4326.


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