eGFR eGFR (ml/min/1.73m2) = 175 x ((plasma creatinine (umol/l)/88.4)-1.154) x age (years)-0.203 x 0.742 if female and x 1.21 if African American

A calculator to determine eGFR can be found here, eGFR Calculator

Prior to 04/12/2006 the factor used was 186 instead of the current 175 value.

The reported eGFR calculation assumes Caucasian race. eGFR estimates should be multiplied by 1.21 in patients of African, African-American, or African-Caribean origin. eGFR calculations have not been validated in other ethnic groups or in subjects of mixed race. (Results in female subjects have had the 0.742 factor applied.)

eGFR estimates between 60 and 89 ml/min/1.73m² should not be considered as evidence of kidney disease unless there is other evidence of chronic kidney damage. eGFR falls with age so many healthy people aged >75 years will have an eGFR of 50 - 60 ml/min/1.73m². Values >90 are reported as >90 ml/min/1.73m². For further information please see www.merseyrenalunits.nhs.uk.

The eGFR equation should not be used in children <18 years, in acute renal failure, pregnancy, oedematous states, muscle wasting states, amputees, malnourished patients.

The variability of the eGFR calculation (the CV coefficient of variation) is about 30% in the populations studied to date. This is much higher than that in other routine tests when the CV usually ranges from 1-10%. eGFR may be affected by food intake.

Because of the limitations of the eGFR measurement and calculation outlined above, some inaccurate and misleading results may be generated.

Click here for CKD NICE clinical guideline 73.

Additional information on MDRD (eGFR) and its clinical use can be found here: MDRD (eGFR) .

ICE requesting info:	ICE panel name	ICE page name	Column	Comment\Advice
	n/a	n/a	n/a	calculated in U&E request

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