Investigation : Methotrexate
Specimen type : Plasma or serum
Spec container : Plain tube 
Volume required : 6 ml
Samples required 24h & 48h post high dose.
Specimens collected from patients who have received glucarpidase (carboxypeptidase G2) as a high dose methotrexate rescue therapy should not be tested for at least 48hrs following the last dose of glucarpidase. These specimens have increased concentrations of DAMPA, a methotrexate metabolite which is known to cross-react with the methotrexate antibody used in this assay.
Please include:
Dose of methotrexate
Date of dose
Time of dose
Number of hrs since administration.

Additional information on methotrexate and its clinical use can be found here: methotrexate.

This analysis is not performed by this laboratory. For local users of these laboratory services, please send your sample to the laboratory and it will be sent to a reference laboratory for analysis.
Assays for Methotrexate are sent here.

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Chem / Haem


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