Troponin T
(Biochemistry)
Investigation : Troponin T
Specimen type : Serum
Spec container : Serum Gel 
Volume required : 5 ml
Reference range : <14 ng/l
Turnaround : <24 hours

Diagnostic Criteria
The universal definition of myocardial infarction includes the "detection of a rise and/or fall of cardiac biomarker values [preferably cardiac troponin (cTn)] with at least one value above the 99th percentile of the reference range". ¹

Sample Timing
High sensitivity Troponin T assays allow for the early diagnosis of myocardial ischaemia. ² Therefore sampling is now recommended at presentation and if required 3 hours later.

Interpretation
Please interpret diagnostic Troponin T requests in line with a full clinical history, ECG changes and the Trustís Troponin T testing policy.

Please see Liverpool Acute Chest Pain Pathway and Proforma for more details.

References
1) Third universal definition of myocardial infarction. European Heart Journal (2012) 33, 2551- 2567
2) Myocardial infarction (acute): Early rule out using high-sensitivity troponin tests (Elecsys Troponin T high-sensitive, ARCHITECT STAT High Sensitive Troponin-I and AccuTnI+3 assays). NICE Diagnostics Guidance. October 2014. (DG15) Link.



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