Aldosterone
 (Biochemistry)
Investigation : Aldosterone
Specimen type : Plasma
Spec container : EDTA 
Volume required : 4 ml
Turnaround : <14 days
Overall Reference Range : Supine 103 - 860pmol/l
Upright103 - 1200pmol/l
Please note Reference Range change 1st December 2014

Direct renin measurement (new methodology from March 2016) can be used in conjuction with aldosterone for an aldosterone renin ratio to aid in the investigation of primary hyperaldosteronism.

APR
(pmol/mIU)		Aldo
(pmol/L)		Interpretation
<30Primary aldosteronism unlikely
≥30<250Primary aldosteronism unlikely (aldo not in range associated with PA)
≥30250 - 399Primary aldosteronism not excluded (aldo typically >400 in PA)
≥30≥400Consistent with primary aldosteronism (suggest confirmatory testing


Please see link for guidance on the management of Primary Aldosteronism.

Factors that affect Aldosterone and Renin concentrations can be found here


Additional information on aldosteroneand its clinical use can be found here: aldosterone.

ICE requesting info:ICE panel nameICE page nameColumnComment\Advice
Chem / Haem
Endo & Oncology
1


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