Acetaminophen intoxications are frequently treated with N-Acetylcysteine. N-Acetylcysteine at therapeutic concentration when used as an antidote and the Acetaminophen metabolite N-acetyl-p-benzoquinone imine (NAPQI) independently may cause falsely low results.

Venipuncture should be performed prior to the administration of Metamizole. Venipuncture immediately after or during the administration of Metamizole may lead to falsely low results.

Cholesterol

Reference range: < 5.0 mmol/L (Heart UK target)

Adults (≥ 16 years old) with total cholesterol >7.5 mmol/L and children (< 16 years old) with total cholesterol >6.7 mmol/L: if there is a family history of vascular disease or high cholesterol, please consider the diagnosis of possible FH and refer to specialist Lipid Clinic for investigation and management. See NICE CG71 and Simon Broome diagnostic criteria.

Overview Cardiovascular disease: risk assessment and reduction, including lipid modification | Guidance | NICE (https://www.nice.org.uk/guidance/ng238)

Link to NICE Guidance on Familial Hypercholesterolaemia: identification and management.

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