Haemoglobinopathy and Thalassaemia screening is used for the investigation of a suspected haemoglobinopathy and/ or thalassaemia. Part of the screening protocols involves the quantitation of HbA2 and HbF levels.

Test	Reference Range
HbA2	2.0 - 3.5 % total Hb
HbF	0.2 - 2.0 % total Hb

Additional Information:
The screening process is able to detect the presence of clinically significant haemoglobin variants e.g. HbS, HbC, HbD, HbE, HbOArab and Hb Lepore, as well as many other haemoglobin variants. If an abnormal haemoglobin variant is detected, it will require further confirmatory testing by a second line of testing methodologies. If this is the case an Interim Haemoglobinopathy report is sent out to meet a 3 day report standard.
https://www.nhs.uk/pregnancy/your-pregnancy-care/screening-for-sickle-cell-and-thalassaemia

Minimum Data Criteria:
The minimum acceptable criteria for accepting a Haemoglobinopathy screening sample is: Full name, DOB, and Unique Identifier (Hospital number, district number, NHS number etc) on sample and request form

Enquires: Contact 0151 706 4333 (Haemoglobinopathy Laboratory at Haematology Dept, Royal Liverpool Hospital

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