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| Investigation | : | Hydroxyprogesterone -17 alpha | ||||||||||
| Specimen type | : | Serum | ||||||||||
| Spec container | : | Serum Gel | ||||||||||
| Volume required | : | 5 ml | ||||||||||
| Reference range | : | <8 nmol/l (adult) | ||||||||||
| Turnaround | : | <14 days | ||||||||||
17 alpha-hydroxyprogesterone is used in the diagnosis of congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency and for monitoring of treatment of CAH. It may also be used in the identification of heterozygotes for CAH and mild late-onset forms. Samples for diagnosis of 21-hydroxylase deficiency should not be taken within 48 hours postpartum and preferably before any steroid therapy. Premature and sick babies may show moderately increased levels of 17 alpha-hydroxyprogesterone.
Contact Duty Endocrine Biochemist for urgent requests.
Age related reference ranges for 17-Hydroxyprogesterone Link.
(Please note: prior to 21/10/2014 the adult reference range was <12 nmol/l).
Additional information on 17-hydroxyprogesterone and its clinical use can be found here: 17-hydroxyprogesterone.