Immunoglobulin Analysis
 (Immunology)
Investigation : Immunoglobulin Analysis
Spec container : Serum Gel 
Volume required : 5ml
Reference range : see table
Turnaround : <5 days

Normal ranges for serum immunoglobulins (Methodology: Turbidimetry)
Age
IgG1 g/L
IgA g/L
IgM g/L
 
Cord 5.2 - 18.0 <0.02 0.02 - 0.2
 
Weeks 0 - 2 5.0 - 17.0 0.01 - 0.08 0.05 - 0.2
2 - 6 5.0 - 17.0 0.01 - 0.08 0.05 - 0.2
6 - 12 2.1 - 7.7 0.05 - 0.4 0.15 - 0.7
 
Months 3 - 6 2.4 - 8.8 0.10 - 0.5 0.2 - 1.0
6 - 9 3.0 - 9.0 0.15 - 0.7 0.4 - 1.6
9 - 12 3.0 - 10.9 0.20 - 0.7 0.6 - 2.1
 
Years 1 - 2 3.1 - 13.8 0.3 - 1.2 0.5 - 2.2
2 - 3 3.7 - 15.8 0.3 - 1.3 0.5 - 2.2
3 - 6 4.9 - 16.1 0.4 - 2.0 0.5 - 2.0
6 - 9 5.4 - 16.1 0.5 - 2.4 0.5 - 1.8
9 - 12 5.4 - 16.1 0.7 - 2.5 0.5 - 1.8
12 - 15 5.4 - 16.1 0.8 - 2.8 0.5 - 1.9
 
15 - 45 6.0 - 16.0 0.8 - 2.8 0.5 - 1.9
over 45 6.0 - 16.0 0.8 - 4.0 0.5 - 2.0

Immunogloblin E
(Methodology: fluorescent enzyme immunoassay)		Reference
Range		UnitsTurnround
Time
IgE (total) 0 -1 year<10kU/l<7 days
1 - 15 years<30kU/l
>15 years<100kU/l
IgE (allergen-specific)2<0.35kUa/ldepends on allergen, common allergens <7; days, rare allergens <21 days

Notes:

  1. Part of the immunoglobulin analysis is performed in the Blood Sciences core laboratory but ALL enquiries should be referred to Immunology.
  2. IgG subclasses are no longer available. If antibody deficiency is suspected, please discuss further investigation with the immunology staff.
  3. Allergens should be individually specified. A blanket request for "RASTS" is unacceptable.


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