| (Microbiology) |
| Investigations | MPOX (Previously called Monkeypox) Mpox is an infectious disease that is caused by infection with a virus called MPXV. There are 2 major genetic groups (clades) of MPXV, clade I (formerly known as Central African or Congo basin clade) and clade II (formerly known as West African clade). Since January 2023, clade II mpox is no longer considered a high consequence infectious disease (HCID) within the UK. Clade I mpox remains an HCID. It is likely that a patient with confirmed or suspected Clade1 mpox will be admitted directly to the Infectious Disease’s Unit. Molecular Tests MPOX PCR |
| Inform lab before sending | Yes suspected clade I cases must be discussed with the ID consultant on-call who will contact the virology consultant to arrange urgent testing. ID may refer suspected clade II cases to Sexual Health. The laboratory does not need to be notified of these samples but the request must clearly indicate suspected clade II. The laboratory will aim to provide same day results for samples received in the laboratory before 9am, otherwise, the sample will be processed the next working day. |
| Specimen type |
Molecular Swabs: Use the Sigma-Virocult swab (GREEN CAPPED) or REMEL swab (RED CAPPED) collection kits. EDTA: 4ml blood into a EDTA (LAVENDER CAPPED) container. Urine: Collected in a sterile leak-proof container. |
| Ideal time to take specimen | See link |
| Labelling requirements | click here |
| How to take the specimen | Discuss with the ID consultant before taking samples. If sampling is advised outside of the ID unit, DO NOT use sharps to deroof blisters or extract fluid from within. Swabs can be taken from the surface of intact blisters/lesions |
| Transport to the laboratory | For suspected clade I cases, contact the virology consultant prior to sampling to arrange safe transport to the laboratory |
| Test Times | MPOX PCR: Daily |
| Turnround | Non-urgent MPOX PCR 3 working days |
| Additional information | For overall guidance please see: https://www.gov.uk/guidance/monkeypox |
| Additional Examination Requests | click here |