Epstein-Barr Virus (EBV)
(Microbiology)
Investigations Epstein-Barr Virus (EBV)
Human herpes viruses are widespread. Epstein-Barr Virus infection is associated with heterophile-antibody positive infectious mononucleosis and some neoplastic disorders.
Serology should not be requested for isolated transaminitis without features of mononucleosis, or on immunocompromised patients.

Serology Tests
EBV antibody screen
EBV IgG (EBNA)
EBV IgG (VCA)
EBV IgM (VCA)

Molecular Tests
EBV PCR
Inform lab before sending No, except for URGENT SAMPLES. Contact the laboratory on 0151 706 4410 to request urgent testing, including pre-transplant serology screening. The laboratory will aim to process urgent EBV PCR Samples the same day, otherwise, the sample will be processed the next working day.
Specimen type Serology
Clotted blood: 5ml Clot activator and separation gel (GOLD CAPPED) container.

Molecular
EDTA: 4ml blood into a EDTA (LAVENDER CAPPED) container.
CSF: Collect at least 0.2ml using the CSF sample collection kit if available. A sterile container is a suitable alternative.
Ideal time to take specimen  
Labelling requirements click here
How to take the specimen  
Transport to the laboratory If transport is delayed then store at +4°C
Test Times EBV serology: Daily
EBV PCR: Daily
Turnround 5 working days
Additional information  
Additional Examination Requests click here


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