Herpes Simplex Virus (HSV)
(Microbiology)
Investigations Herpes Simplex Virus (HSV)
Human herpes viruses are widespread. Herpes simplex viruses types 1 and 2 cause both oral and genital infections. The virus is a common cause of aseptic meningitis and may also cause pneumonitis in immunocompromised patients.

Serology Tests
HSV-1/2 IgG

Molecular Tests
HSV PCR
Inform lab before sending No, except for URGENT SAMPLES. Contact the laboratory on 0151 706 4410 to request urgent testing. The laboratory will aim to provide same day results for samples received in the laboratory before 9am, otherwise, the sample will be processed the next working day.
Specimen type Serology
Clotted blood: 5ml Clot activator and separation gel (GOLD CAPPED) container.

Molecular
Swabs: Use the Sigma-Virocult swab (GREEN CAPPED) or REMEL swab (RED CAPPED) collection kits.
EDTA: 10ml blood into a potassium EDTA (RED CAPPED) container.
CSF: Collect at least 0.2ml using the CSF sample collection kit if available. A sterile container is a suitable alternative.
Bronchoalveolar lavage:Collected in a sterile leak-proof container.
Ideal time to take specimen  
Labelling requirements click here
How to take the specimen For investigation of vesicular skin lesions, rub the top off a vesicle with a sterile swab to absorb the vesicle fluid.
If necessary, burst the vesicle with a sterile needle and absorb the vesicle fluid with the swab.
Transport to the laboratory If transport is delayed then store at +4°C
Test Times Serology: Weekly
HSV PCR: Daily
Turnround Serology: 5 working days
HSV PCR 3 working days
Additional information Bacterial Transport Media (blue swabs), cannot be processed by molecular diagnostic methods.
Additional Examination Requests click here


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